These days, CBD is being passed off as a sort of help-all for a variety of different illnesses and symptoms. While there are many ways that CBD products can positively affect a person’s health and well-being, it might not be something that every single person should jump into without considering certain factors, such as CBD interactions. Just like with anything else one might put into their bodies, it is important to know that you can always run the risk of interactions with other kinds of medication that you take. In the same vein, asking questions like “Can CBD oil interact with medications?” before consuming it could save you a lot of strife in the future.

So, what is the answer? Can CBD oil interact with medications?
The short answer is yesÑthere are some CBD interactions with certain kinds of medications. CBD has the potential to inhibit the cytochrome known as the P450 enzyme, which is a compound whose involvement in your system makes it responsible for helping to metabolize a variety of drugs. You may have heard about some people being unable to consume grapefruit if they are on certain medications, especially shortly before or after consuming their medicine, and that is because grapefruit also inhibits the same group of enzymes that CBD oil can.

Is it Safe to Take CBD with Other Medications? Because the P450 enzyme is in control of metabolizing as much as 60 percent of most prescribed drugs, coming into contact and interacting with CBD that has been introduced causes it to have to struggle to break down the medicine in order to deliver it to the body where it is needed. At the same time, because so much is going toward that enzyme breaking down other medicines, it also has a harder time breaking down CBD, meaning you might not be getting all that you need wen you take it.

It can either increase or reduce the effects of certain other drugs; if your body metabolizes it too slowly, you could end up with more of your medicine in your system at a single time, even if you take your normal nose, which could cause adverse or even sometimes harmful side effects. Some of the substances can also make the work of the CYP450 enzyme family speed up, meaning it could metabolize it too quickly, which could also mean you don’t have enough of the medicine in your body at one time. All of this means patients should consult with their physicians before taking any CBD as an add-on therapy.

What kind of drug interactions can occur with CBD?
There are a variety of medications that can interact with your CBD, including but not limited to:

  • Antidepressants like fluoxetine or Prozac
  • Heart medicines including some calcium channel blockers
  • Macrolide antibiotics including clarithromycin and erythromycin
  • Medications that cause drowsiness, such as benzodiazepines and antipsychotics

For those looking to enjoy the purported benefits of CBD but are concerned about CBD interactions, check with your doctor to find out if it is safe for you to use, or what other alternatives to CBD oil might be able to take its place if not, such as creams.